Cheryl convinces Larry that they should take in a family who lost their home in a hurricane, and Larry tries to avoid two parties.

A new home for the Davids comes with another houseguest; Larry complains about a dry-cleaning mishap to Sen. Barbara Boxer (D-Cal.) after his prized Yankees jersey is lost; Ted Danson’s anonymity irks Larry at a philanthropic gala.

Larry takes offense at other people’s shopping methods; Marty Funkhouser mourns the loss of his mother, but is angered by the lack of flowers at her memorial.

Larry comes to regret his decision to get Richard Lewis's girlfriend a job next to the office's bathroom; Larry's political acumen needs sharpening.

A limo driver’s faux pas at Ted Danson’s birthday party results in Larry driving John McEnroe to a Paul McCartney concert; Larry reconsiders his position in a cemetery plot with his wife and friends.

Loretta and Leon have job interviews; Jeff’s exterminator bugs Larry to take him to a middle-school production of a Greasea ; Larry inadvertently insults a hearing-impaired woman’s dog.

Cheryl is on a flight back home from Florida, and during the trip, the flight encounters horrific weather. Fearing for her life, she calls Larry, who has the Tivo guy over at his house and as Cheryl proclaims her love for him, he tells her to call back because the Tivo guy is there. For the rest of the week Cheryl holds a grudge against Larry.

Larry's attempt to do something nice for Auntie Rae backfires; an opportunity arises for Larry when Jeff's treated for a sleeping disorder.

Larry works hard to show Cheryl that New Larry is the perfect man for her. When some questionable advice from his therapist goes horribly wrong during a date, Cheryl tells him that she has to consult with her therapist before making any decisions about their future. Feeling that his back is against the wall, Larry decides that he must intervene with Cheryl's therapist and enlists the help of his own.

With his recent failed attempt to rekindle Cheryl's affections weighing heavily upon him, Larry is in a deep funk. But Jeff's daughter's Bat Mitzvah is coming up, and Cheryl will be attending with her new romantic interest. Larry needs to find a date. He also needs to find what's irritating his anus, and makes an appointment with a gastroenterologist. A disagreement with the office receptionist starts a rumor about Larry and sexual deviance with furry rodents. But while in the waiting room, he meets Paula, an attractive and charming woman who agrees to go on a date with him. But in traditional Larry fashion, he screws up the date and she goes home early. At the last moment, Larry invites Loretta Black to the Bat Mitzvah. While at the event, he takes the opportunity to publicly address the sexual deviance-rodent issue.